Body Complexion and Circulating Lipids in the Risk of TDP-43 Related Disorders
ObjectiveFrontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two distinct degenerative disorders with overlapping genetics, clinical manifestations, and pathology, including the presence of TDP-43 aggregates in nearly 50% of patients with FTD and 98% of all patients with ALS.Here, we evaluate whether different genetically pred